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Typical neuropathological features of AD include the deposition of beta-amyloid (A) into neuroinflammatory plaques, intracellular aggregates of Tau protein in neurofibrillary tangles, synaptic loss, neuroinflammation, and neuronal death

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The extrinsic factors include physical activity [10], dietary intake [11] and stem cell transplantation [12]

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Designed to support metabolic flexibility, cellular renewal processes, and the signaling systems involved in healthy metabolic aging

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